Clinical implications of irregular ADMET properties with levodopa and other antiparkinson's drugs
نویسندگان
چکیده
منابع مشابه
Clinical implications of irregular ADMET properties with levodopa and other antiparkinson's drugs.
INTRODUCTION Parkinson's disease is a neurodegenerative disorder characterized by the loss of striatal dopaminergic neurons. Besides the improvement of the dopaminergic loss, the treatment focuses on non-dopaminergic medication targeting motor and non-motor symptoms, and on the development of neuroprotective medication. A good knowledge of the properties of the compounds used is essential not o...
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ژورنال
عنوان ژورنال: Expert Opinion on Drug Metabolism & Toxicology
سال: 2014
ISSN: 1742-5255,1744-7607
DOI: 10.1517/17425255.2014.878702